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Hippocampal [(18)F]flortaucipir BP(ND) corrected for possible spill-in of the choroid plexus retains strong clinico-pathological relationships

BACKGROUND: Off-target [(18)F]flortaucipir (tau) PET binding in the choroid plexus causes spill-in into the nearby hippocampus, which may influence the correlation between [(18)F]flortaucipir binding and measures of cognition. Previously, we showed that partial volume correction (combination of Van...

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Detalles Bibliográficos
Autores principales: Wolters, Emma E, Ossenkoppele, Rik, Golla, Sandeep SV, Verfaillie, Sander CJ, Timmers, Tessa, Visser, Denise, Tuncel, Hayel, Coomans, Emma M, Windhorst, Albert D, Scheltens, Philip, van der Flier, Wiesje M, Boellaard, Ronald, van Berckel, Bart NM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920114/
https://www.ncbi.nlm.nih.gov/pubmed/31835238
http://dx.doi.org/10.1016/j.nicl.2019.102113