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Rhubarb-Evoke Mucus Secretion through Aggregation and Degranulation of Mast Cell in the Colon of Rat: In vivo and ex vivo studies

Rhubarb is commonly used to treat constipation in China for its function of promoting intestinal movement and optimum water content in feces. However, its mechanism of mucus secretion is vague. The aim of the study is to investigate the role of mast cells and enteric neurons in rhubarb extract (RE)-...

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Detalles Bibliográficos
Autores principales: Wu, Di, Xue, Xiaowei, Gao, Chenchen, Liu, Yuehong, Wang, Tiantian, Li, Lisheng, Tong, Xuehong, Li, Feng, Xu, Jingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920142/
https://www.ncbi.nlm.nih.gov/pubmed/31852975
http://dx.doi.org/10.1038/s41598-019-55937-7