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Purβ promotes hepatic glucose production by increasing Adcy6 transcription

OBJECTIVE: Enhanced glucagon signaling and hepatic glucose production (HGP) can account for hyperglycemia in patients with obesity and type 2 diabetes. However, the detailed molecular mechanisms underlying the enhanced HGP in these patients are not fully understood. Here, we identify Purβ as a posit...

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Detalles Bibliográficos
Autores principales: Jia, Linna, Jiang, Yunfeng, Li, Xinzhi, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920194/
https://www.ncbi.nlm.nih.gov/pubmed/31918924
http://dx.doi.org/10.1016/j.molmet.2019.11.008