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Long interspersed element-1 ribonucleoprotein particles protect telomeric ends in alternative lengthening of telomeres dependent cells

Malignant cells ensure telomere maintenance by the alternative lengthening of telomeres (ALT) in the absence of telomerase activity (TA). The retrotransposons “long interspersed nuclear element-1” (LINE-1, L1) are expressed in malignant cells and are primarily known to contribute to complex karyotyp...

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Detalles Bibliográficos
Autores principales: Aschacher, Thomas, Wolf, Brigitte, Aschacher, Olivia, Enzmann, Florian, Laszlo, Viktoria, Messner, Barbara, Türkcan, Adrian, Weis, Serge, Spiegl-Kreinecker, Sabine, Holzmann, Klaus, Laufer, Günther, Ehrlich, Marek, Bergmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920197/
https://www.ncbi.nlm.nih.gov/pubmed/31846834
http://dx.doi.org/10.1016/j.neo.2019.11.002