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Accumulation of Nucleolar Inorganic Polyphosphate Is a Cellular Response to Cisplatin-Induced Apoptosis

The chemotherapeutic drug cisplatin, which targets DNA, serves as one of the main staples in cancer treatment. Yet, the therapeutic application of cisplatin is limited by two major challenges: the occurrence of reversible and irreversible side effects due to non-specific toxicity, and the intrinsic...

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Detalles Bibliográficos
Autores principales: Xie, Lihan, Rajpurkar, Asavari, Quarles, Ellen, Taube, Nicole, Rai, Akash S., Erba, Jake, Sliwinski, Benjamin, Markowitz, Moses, Jakob, Ursula, Knoefler, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920253/
https://www.ncbi.nlm.nih.gov/pubmed/31921667
http://dx.doi.org/10.3389/fonc.2019.01410