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Pitfalls and solutions of the fully-automated radiosynthesis of [(11)C]metoclopramide

BACKGROUND: [(11)C]Metoclopramide is a new radiotracer for investigating the activity of P-glycoprotein at the blood-brain barrier. A highly stable and reproducible radiosynthesis is a prerequisite for clinical studies applying [(11)C]metoclopramide or other (11)C-labelled radiotracers, therefore al...

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Detalles Bibliográficos
Autores principales: Pichler, Verena, Ozenil, Marius, Bamminger, Karsten, Vraka, Chrysoula, Hacker, Marcus, Langer, Oliver, Wadsak, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920278/
https://www.ncbi.nlm.nih.gov/pubmed/31853677
http://dx.doi.org/10.1186/s41181-019-0083-2