Targeting Extracellular miR-21-TLR7 Signaling Provides Long-Lasting Analgesia in Osteoarthritis

Osteoarthritis (OA) is the most prevalent joint disorder associated with severe chronic pain. Although synovial inflammation is well correlated with pain severity, the molecular mechanism responsible for OA pain remains unclear. Here, we show that extracellular miR-21 released from synovial tissue m...

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Detalles Bibliográficos
Autores principales: Hoshikawa, Naoya, Sakai, Atsushi, Takai, Shinro, Suzuki, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920297/
https://www.ncbi.nlm.nih.gov/pubmed/31841992
http://dx.doi.org/10.1016/j.omtn.2019.11.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920297/
https://www.ncbi.nlm.nih.gov/pubmed/31841992
http://dx.doi.org/10.1016/j.omtn.2019.11.011

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