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Development of a Novel DNA Oligonucleotide Targeting Low-Density Lipoprotein Receptor
Low-density lipoprotein receptor (LDL-R) is a cell surface receptor protein expressed in a variety of solid cancers, including lung, colon, breast, brain, and liver, and therefore it opens up opportunities to deliver lysosome-sensitive anti-cancer agents, especially synthetic nucleic acid-based ther...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920325/ https://www.ncbi.nlm.nih.gov/pubmed/31841991 http://dx.doi.org/10.1016/j.omtn.2019.11.004 |