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Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice

TLR4 is a transmembrane receptor of the innate immune system that recognizes LPS from gram-negative bacteria. Its stimulation induces pro-inflammatory responses and modulates adaptive immunity. Our aim is to determine the role of TLR4 in the activation and proliferation of T lymphocytes in the onset...

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Detalles Bibliográficos
Autores principales: Alibashe-Ahmed, Mohamed, Brioudes, Estelle, Reith, Walter, Bosco, Domenico, Berney, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920362/
https://www.ncbi.nlm.nih.gov/pubmed/31852918
http://dx.doi.org/10.1038/s41598-019-55521-z