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Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice
TLR4 is a transmembrane receptor of the innate immune system that recognizes LPS from gram-negative bacteria. Its stimulation induces pro-inflammatory responses and modulates adaptive immunity. Our aim is to determine the role of TLR4 in the activation and proliferation of T lymphocytes in the onset...
Autores principales: | Alibashe-Ahmed, Mohamed, Brioudes, Estelle, Reith, Walter, Bosco, Domenico, Berney, Thierry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920362/ https://www.ncbi.nlm.nih.gov/pubmed/31852918 http://dx.doi.org/10.1038/s41598-019-55521-z |
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