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Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7

Skeletal muscle stem cells, called satellite cells and defined by the transcription factor PAX7, are responsible for postnatal muscle growth, homeostasis and regeneration. Attempts to utilize the regenerative potential of muscle stem cells for therapeutic purposes so far failed. We previously establ...

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Detalles Bibliográficos
Autores principales: Marg, Andreas, Escobar, Helena, Karaiskos, Nikos, Grunwald, Stefanie A., Metzler, Eric, Kieshauer, Janine, Sauer, Sascha, Pasemann, Diana, Malfatti, Edoardo, Mompoint, Dominique, Quijano-Roy, Susanna, Boltengagen, Anastasiya, Schneider, Joanna, Schülke, Markus, Kunz, Séverine, Carlier, Robert, Birchmeier, Carmen, Amthor, Helge, Spuler, Andreas, Kocks, Christine, Rajewsky, Nikolaus, Spuler, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920394/
https://www.ncbi.nlm.nih.gov/pubmed/31852888
http://dx.doi.org/10.1038/s41467-019-13650-z