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DNA Methylation Activates TP73 Expression in Hepatocellular Carcinoma and Gastrointestinal Cancer

The complexity of TP73 expression and its functionality, as well as the role of TP73 in tumorigenesis, unlike its cousin TP53, which is an established tumor suppressor, have remained elusive to date. In this study, we isolated two stem cell lines (HepCY & HepCO) from normal young and old human l...

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Detalles Bibliográficos
Autores principales: Yao, Zhixing, Di Poto, Cristina, Mavodza, Grace, Oliver, Everett, Ressom, Habtom W., Sherif, Zaki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920427/
https://www.ncbi.nlm.nih.gov/pubmed/31852961
http://dx.doi.org/10.1038/s41598-019-55945-7