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Mapping of Shigella flexneri’s tissue distribution and type III secretion apparatus activity during infection of the large intestine of guinea pigs

Shigella spp. are bacterial pathogens that invade the human colonic mucosa using a type III secretion apparatus (T3SA), a proteinaceous device activated upon contact with host cells. Active T3SAs translocate proteins that carve the intracellular niche of Shigella spp. Nevertheless, the activation st...

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Detalles Bibliográficos
Autores principales: Nigro, Giulia, Arena, Ellen T, Sachse, Martin, Moya-Nilges, Maryse, Marteyn, Benoit S, Sansonetti, Philippe J, Campbell-Valois, F-X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920510/
https://www.ncbi.nlm.nih.gov/pubmed/31578543
http://dx.doi.org/10.1093/femspd/ftz054