Stochastic Expansions Maintain the Clonal Stability of CD8(+) T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus
CMV is an obligate and persistent intracellular pathogen that continually drives the production of highly differentiated virus-specific CD8(+) T cells in an Ag-dependent manner, a phenomenon known as memory inflation. Extensive proliferation is required to generate and maintain inflationary CD8(+) T...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920548/ https://www.ncbi.nlm.nih.gov/pubmed/31818981 http://dx.doi.org/10.4049/jimmunol.1900455 |