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Lipopolysaccharide Increases Cortical Kynurenic Acid and Deficits in Reference Memory in Mice
Kynurenic acid (KYNA), a glial-derived metabolite of tryptophan metabolism, is an antagonist of the alpha 7 nicotinic acetylcholine receptor and the glycine-binding site of N-methyl-d-aspartate (NMDA) receptors. Kynurenic acid levels are increased in both the brain and cerebrospinal fluid of several...
Autores principales: | Peyton, Lee, Oliveros, Alfredo, Tufvesson-Alm, Maximilian, Schwieler, Lilly, Starski, Phillip, Engberg, Göran, Erhardt, Sopie, Choi, Doo-Sup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920585/ https://www.ncbi.nlm.nih.gov/pubmed/31896932 http://dx.doi.org/10.1177/1178646919891169 |
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