Unique anabolic action of stem cell gene therapy overexpressing PDGFB-DSS6 fusion protein in OVX osteoporosis mouse model

In the present study we sought to improve the efficacy and safety of our Sca1(+) PDGFB stem cell gene therapy for osteoporosis in ovariectomized (OVX) mouse model. This therapy is administered by marrow transplantation. We established the promise of this approach by previously showing that this ther...

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Detalles Bibliográficos
Autores principales: Chen, Wanqiu, Wasnik, Samiksha, Fu, Yawen, Aranda, Leslie, Rundle, Charles H., Lau, Kin-Hing William, Baylink, David J., Zhang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920713/
https://www.ncbi.nlm.nih.gov/pubmed/31886323
http://dx.doi.org/10.1016/j.bonr.2019.100236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920713/
https://www.ncbi.nlm.nih.gov/pubmed/31886323
http://dx.doi.org/10.1016/j.bonr.2019.100236

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