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Highly Water-Soluble Solid Dispersions of Honokiol: Preparation, Solubility, and Bioavailability Studies and Anti-Tumor Activity Evaluation

Honokiol (HK), a well-tolerated natural product, has many multiple pharmacological activities. However, its poor water solubility and low bioavailability limit its clinical application and development. The aim of this research was to prepare the solid dispersion (SD) formulation of honokiol (HK) wit...

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Detalles Bibliográficos
Autores principales: Wang, Li, Wu, Weiwei, Wang, Lingling, Wang, Lu, Zhao, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920775/
https://www.ncbi.nlm.nih.gov/pubmed/31683964
http://dx.doi.org/10.3390/pharmaceutics11110573