Replenishment of Hepatitis B Virus cccDNA Pool Is Restricted by Baseline Expression of Host Restriction Factors In Vitro

Background: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) is the major cause of viral persistence in patients with chronic HBV infection. Understanding the mechanisms underlying stability and persistence of HBV cccDNA in hepatocytes is critical for developing novel therapeutics...

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Detalles Bibliográficos
Autores principales: Brezgin, Sergey, Kostyusheva, Anastasiia, Bayurova, Ekaterina, Gordeychuk, Ilya, Isaguliants, Maria, Goptar, Irina, Nikiforova, Anastasiia, Smirnov, Valery, Volchkova, Elena, Glebe, Dieter, Kostyushev, Dmitry, Chulanov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920784/
https://www.ncbi.nlm.nih.gov/pubmed/31698767
http://dx.doi.org/10.3390/microorganisms7110533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920784/
https://www.ncbi.nlm.nih.gov/pubmed/31698767
http://dx.doi.org/10.3390/microorganisms7110533

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