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Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules

The poor aqueous solubility of existing and emerging drugs is a major issue faced by the pharmaceutical industry. Water-miscible organic solvents, termed co-solvents, can be used to enhance the solubility of poorly soluble substances. Typically, drugs with poor aqueous solubility and Log P > 3 ar...

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Detalles Bibliográficos
Autores principales: Kearney, Mary-Carmel, McKenna, Peter E., Quinn, Helen L., Courtenay, Aaron J., Larrañeta, Eneko, Donnelly, Ryan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920785/
https://www.ncbi.nlm.nih.gov/pubmed/31766145
http://dx.doi.org/10.3390/pharmaceutics11110605