Synthesis of β-d-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential

Pseudomonas aeruginosa is an opportunistic human pathogen associated with cystic fibrosis. This bacterium produces, among other virulence factors, a soluble d-galactose-specific lectin PA-IL (LecA). PA-IL plays an important role in the adhesion to the host cells and is also cytotoxic. Therefore, thi...

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Detalles Bibliográficos
Autores principales: Malinovská, Lenka, Le, Son Thai, Herczeg, Mihály, Vašková, Michaela, Houser, Josef, Fujdiarová, Eva, Komárek, Jan, Hodek, Petr, Borbás, Anikó, Wimmerová, Michaela, Csávás, Magdolna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920806/
https://www.ncbi.nlm.nih.gov/pubmed/31683947
http://dx.doi.org/10.3390/biom9110686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920806/
https://www.ncbi.nlm.nih.gov/pubmed/31683947
http://dx.doi.org/10.3390/biom9110686

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