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Synthesis of β-d-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential
Pseudomonas aeruginosa is an opportunistic human pathogen associated with cystic fibrosis. This bacterium produces, among other virulence factors, a soluble d-galactose-specific lectin PA-IL (LecA). PA-IL plays an important role in the adhesion to the host cells and is also cytotoxic. Therefore, thi...
Autores principales: | Malinovská, Lenka, Le, Son Thai, Herczeg, Mihály, Vašková, Michaela, Houser, Josef, Fujdiarová, Eva, Komárek, Jan, Hodek, Petr, Borbás, Anikó, Wimmerová, Michaela, Csávás, Magdolna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920806/ https://www.ncbi.nlm.nih.gov/pubmed/31683947 http://dx.doi.org/10.3390/biom9110686 |
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