Nanomedicine against Aβ Aggregation by β–Sheet Breaker Peptide Delivery: In Vitro Evidence

The accumulation of amyloid β (Aβ) triggers a cascade of toxic events in Alzheimer’s disease (AD). The KLVFF peptide can interfere with Aβ aggregation. However, the peptide suffers from poor bioavailability and the inability to cross the blood–brain barrier. In this work, we study the possibility of...

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Detalles Bibliográficos
Autores principales: Pederzoli, Francesca, Ruozi, Barbara, Duskey, Jason, Hagmeyer, Simone, Sauer, Ann Katrin, Grabrucker, Stefanie, Coelho, Romina, Oddone, Natalia, Ottonelli, Ilaria, Daini, Eleonora, Zoli, Michele, Vandelli, Maria Angela, Tosi, Giovanni, Grabrucker, Andreas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920811/
https://www.ncbi.nlm.nih.gov/pubmed/31683907
http://dx.doi.org/10.3390/pharmaceutics11110572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920811/
https://www.ncbi.nlm.nih.gov/pubmed/31683907
http://dx.doi.org/10.3390/pharmaceutics11110572

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