Mutation S115T in IMP-Type Metallo-β-Lactamases Compensates for Decreased Expression Levels Caused by Mutation S119G

(1) Background: Metallo-β-lactamases (MBLs) have raised concerns due to their ability to inactivate carbapenems and newer generation cephalosporins and the absence of clinically available MBL inhibitors. Their genes are often transferred horizontally, and the number of MBL variants has grown exponen...

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Detalles Bibliográficos
Autores principales: Zhang, Charles J., Faheem, Mohammad, Dang, Paulie, Morris, Monica N., Kumar, Pooja, Oelschlaeger, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920813/
https://www.ncbi.nlm.nih.gov/pubmed/31718049
http://dx.doi.org/10.3390/biom9110724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920813/
https://www.ncbi.nlm.nih.gov/pubmed/31718049
http://dx.doi.org/10.3390/biom9110724

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