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Development of Injectable PEGylated Liposome Encapsulating Disulfiram for Colorectal Cancer Treatment
Disulfiram (DS), an anti-alcoholism medicine, shows strong anti-cancer activity in the laboratory, but the application in clinics for anti-cancer therapy has been limited by its prompt metabolism. Conventional liposomes have shown limited ability to protect DS. Therefore, the aim of this study is to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920821/ https://www.ncbi.nlm.nih.gov/pubmed/31739556 http://dx.doi.org/10.3390/pharmaceutics11110610 |