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Co-Encapsulation of Chlorin e6 and Chemotherapeutic Drugs in a PEGylated Liposome Enhance the Efficacy of Tumor Treatment: Pharmacokinetics and Therapeutic Efficacy

Long-circulating PEG-modified liposome has been shown to improve pharmacokinetic properties and reduce systemic toxicity in cancer treatment. However, drug bioavailability from liposome remains a major challenge to the improvement of its therapeutic efficacy. Previously, we designed a PEGylated dual...

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Detalles Bibliográficos
Autores principales: Peng, Po-Chun, Hong, Ruey-Long, Tsai, Tsuimin, Chen, Chin-Tin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920861/
https://www.ncbi.nlm.nih.gov/pubmed/31744218
http://dx.doi.org/10.3390/pharmaceutics11110617