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NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV

The recombination-activating genes (RAGs) and the DNA cross-link repair 1C gene (DCLRE1C) encode the enzymes RAG1, RAG2 and Artemis. They are critical components of the V(D)J recombination machinery. V(D)J recombination is well known as a prerequisite for the development and antigen diversity of T a...

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Detalles Bibliográficos
Autores principales: Wu, Zeguang, Subramanian, Narmadha, Jacobsen, Eva-Maria, Laib Sampaio, Kerstin, van der Merwe, Johannes, Hönig, Manfred, Mertens, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920872/
https://www.ncbi.nlm.nih.gov/pubmed/31717670
http://dx.doi.org/10.3390/microorganisms7110546