Mitochondria-Mediated Programmed Cell Death in Saccharomyces Cerevisiae Induced by Betulinic Acid is Accelerated by the Deletion of PEP4 Gene

In this work, using Saccharomyces cerevisiae as a model, we showed that BetA could inhibit cell proliferation and lead to lethal cytotoxicity accompanying programmed cell death (PCD). Interestingly, it was found that vacuolar protease Pep4p played a pivotal role in BetA-induced S. cerevisiae PCD. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Hongyun, Shu, Qin, Lou, Hanghang, Chen, Qihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920885/
https://www.ncbi.nlm.nih.gov/pubmed/31703462
http://dx.doi.org/10.3390/microorganisms7110538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920885/
https://www.ncbi.nlm.nih.gov/pubmed/31703462
http://dx.doi.org/10.3390/microorganisms7110538

Ejemplares similares