Structural Insights into Escherichia coli Shiga Toxin (Stx) Glycosphingolipid Receptors of Porcine Renal Epithelial Cells and Inhibition of Stx-Mediated Cellular Injury Using Neoglycolipid-Spiked Glycovesicles

Shiga toxin (Stx) producing Escherichia coli (STEC) cause the edema disease in pigs by releasing the swine-pathogenic Stx2e subtype as the key virulence factor. Stx2e targets endothelial cells of animal organs including the kidney harboring the Stx receptor glycosphingolipids (GSLs) globotriaosylcer...

Descripción completa

Detalles Bibliográficos
Autores principales: Detzner, Johanna, Gloerfeld, Caroline, Pohlentz, Gottfried, Legros, Nadine, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920957/
https://www.ncbi.nlm.nih.gov/pubmed/31752441
http://dx.doi.org/10.3390/microorganisms7110582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920957/
https://www.ncbi.nlm.nih.gov/pubmed/31752441
http://dx.doi.org/10.3390/microorganisms7110582

Ejemplares similares