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Structural Insights into Escherichia coli Shiga Toxin (Stx) Glycosphingolipid Receptors of Porcine Renal Epithelial Cells and Inhibition of Stx-Mediated Cellular Injury Using Neoglycolipid-Spiked Glycovesicles

Shiga toxin (Stx) producing Escherichia coli (STEC) cause the edema disease in pigs by releasing the swine-pathogenic Stx2e subtype as the key virulence factor. Stx2e targets endothelial cells of animal organs including the kidney harboring the Stx receptor glycosphingolipids (GSLs) globotriaosylcer...

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Detalles Bibliográficos
Autores principales:	Detzner, Johanna, Gloerfeld, Caroline, Pohlentz, Gottfried, Legros, Nadine, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920957/ https://www.ncbi.nlm.nih.gov/pubmed/31752441 http://dx.doi.org/10.3390/microorganisms7110582

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