Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers

Self-assembly of proteins to β-sheet rich amyloid fibrils is commonly observed in various neurodegenerative diseases. However, amyloid also occurs in the extracellular matrix of bacterial biofilm, which protects bacteria from environmental stress and antibiotics. Many Pseudomonas strains produce fun...

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Detalles Bibliográficos
Autores principales: Najarzadeh, Zahra, Mohammad-Beigi, Hossein, Nedergaard Pedersen, Jannik, Christiansen, Gunna, Sønderby, Thorbjørn Vincent, Shojaosadati, Seyed Abbas, Morshedi, Dina, Strømgaard, Kristian, Meisl, Georg, Sutherland, Duncan, Skov Pedersen, Jan, Otzen, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920965/
https://www.ncbi.nlm.nih.gov/pubmed/31717821
http://dx.doi.org/10.3390/biom9110659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920965/
https://www.ncbi.nlm.nih.gov/pubmed/31717821
http://dx.doi.org/10.3390/biom9110659

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