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Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers
Self-assembly of proteins to β-sheet rich amyloid fibrils is commonly observed in various neurodegenerative diseases. However, amyloid also occurs in the extracellular matrix of bacterial biofilm, which protects bacteria from environmental stress and antibiotics. Many Pseudomonas strains produce fun...
Autores principales: | Najarzadeh, Zahra, Mohammad-Beigi, Hossein, Nedergaard Pedersen, Jannik, Christiansen, Gunna, Sønderby, Thorbjørn Vincent, Shojaosadati, Seyed Abbas, Morshedi, Dina, Strømgaard, Kristian, Meisl, Georg, Sutherland, Duncan, Skov Pedersen, Jan, Otzen, Daniel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920965/ https://www.ncbi.nlm.nih.gov/pubmed/31717821 http://dx.doi.org/10.3390/biom9110659 |
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