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Doxorubicin and Varlitinib Delivery by Functionalized Gold Nanoparticles Against Human Pancreatic Adenocarcinoma

The aim of this study was to develop drug delivery nanosystems based on pegylated gold nanoparticles (PEGAuNPs) for a combination against pancreatic cancer cells. Doxorubicin and varlitinib, an anthracycline and a tyrosine kinase inhibitor respectively, were conjugated with gold nanoparticles. The s...

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Detalles Bibliográficos
Autores principales: Coelho, Sílvia Castro, Reis, Daniel Pires, Pereira, Maria Carmo, Coelho, Manuel A. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920992/
https://www.ncbi.nlm.nih.gov/pubmed/31652942
http://dx.doi.org/10.3390/pharmaceutics11110551