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Preparation, Characterization, and In Vivo Pharmacokinetic Study of the Supercritical Fluid-Processed Liposomal Amphotericin B
Here, we aimed to prepare and optimize liposomal amphotericin B (AmB) while using the supercritical fluid of carbon dioxide (SCF-CO(2)) method and investigate the characteristics and pharmacokinetics of the SCF-CO(2)-processed liposomal AmB. Liposomes containing phospholipids, ascorbic acid (vit C),...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921013/ https://www.ncbi.nlm.nih.gov/pubmed/31717352 http://dx.doi.org/10.3390/pharmaceutics11110589 |