The Loop of the TPR1 Subdomain of Phi29 DNA Polymerase Plays a Pivotal Role in Primer-Terminus Stabilization at the Polymerization Active Site

Bacteriophage Phi29 DNA polymerase belongs to the protein-primed subgroup of family B DNA polymerases that use a terminal protein (TP) as a primer to initiate genome replication. The resolution of the crystallographic structure showed that it consists of an N-terminal domain with the exonuclease act...

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Detalles Bibliográficos
Autores principales: del Prado, Alicia, Santos, Eugenia, Lázaro, José M., Salas, Margarita, de Vega, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921018/
https://www.ncbi.nlm.nih.gov/pubmed/31653090
http://dx.doi.org/10.3390/biom9110648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921018/
https://www.ncbi.nlm.nih.gov/pubmed/31653090
http://dx.doi.org/10.3390/biom9110648

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