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Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration

One of the most challenging aspects of treating disorders of the central nervous system (CNS) is the efficient delivery of drugs to their targets within the brain. Only a small fraction of drugs is able to cross the blood–brain barrier (BBB) under physiological conditions, and this observation has p...

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Detalles Bibliográficos
Autores principales: Lochhead, Jeffrey J., Davis, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921024/
https://www.ncbi.nlm.nih.gov/pubmed/31726721
http://dx.doi.org/10.3390/pharmaceutics11110598