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Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration
One of the most challenging aspects of treating disorders of the central nervous system (CNS) is the efficient delivery of drugs to their targets within the brain. Only a small fraction of drugs is able to cross the blood–brain barrier (BBB) under physiological conditions, and this observation has p...
Autores principales: | Lochhead, Jeffrey J., Davis, Thomas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921024/ https://www.ncbi.nlm.nih.gov/pubmed/31726721 http://dx.doi.org/10.3390/pharmaceutics11110598 |
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