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Combination of Gemcitabine with Cell-Penetrating Peptides: A Pharmacokinetic Approach Using in Silico Tools

Gemcitabine is an anticancer drug used to treat a wide range of solid tumors and is a first line treatment for pancreatic cancer. Our group has previously developed novel conjugates of gemcitabine with cell-penetrating peptides (CPP), and here we report some preliminary data regarding the pharmacoki...

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Detalles Bibliográficos
Autores principales: Ferreira, Abigail, Lapa, Rui, Vale, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921036/
https://www.ncbi.nlm.nih.gov/pubmed/31690028
http://dx.doi.org/10.3390/biom9110693