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Folate Receptor-Targeting and Reactive Oxygen Species-Responsive Liposomal Formulation of Methotrexate for Treatment of Rheumatoid Arthritis

Multifunctional nanomedicines with active targeting and stimuli-responsive drug release function utilizing pathophysiological features of the disease are regarded as an effective strategy for treatment of rheumatoid arthritis (RA). Under the inflammatory environment of RA, activated macrophages reve...

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Detalles Bibliográficos
Autores principales: Chen, Minglei, Daddy J.C., Kambere Amerigos, Su, Zhigui, Guissi, Nida El Islem, Xiao, Yanyu, Zong, Li, Ping, Qineng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921073/
https://www.ncbi.nlm.nih.gov/pubmed/31698794
http://dx.doi.org/10.3390/pharmaceutics11110582