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Systematically Prioritizing Candidates in Genome-Based Drug Repurposing

Drug repurposing is the application of approved drugs to treat diseases separate and distinct from their original indications. Herein, we define the scope of all practical precision drug repurposing using DrugBank, a publicly available database of pharmacological agents, and BioVU, a large, de-ident...

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Detalles Bibliográficos
Autores principales: Challa, Anup P., Lavieri, Robert R., Lewis, Judith T., Zaleski, Nicole M., Shirey-Rice, Jana K., Harris, Paul A., Aronoff, David M., Pulley, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921094/
https://www.ncbi.nlm.nih.gov/pubmed/31769998
http://dx.doi.org/10.1089/adt.2019.950