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Pharmacogenomic network analysis of the gene-drug interaction landscape underlying drug disposition

In recent decades the identification of pharmacogenomic gene-drug associations has evolved tremendously. Despite this progress, a major fraction of the heritable inter-individual variability remains elusive. Higher-dimensional phenomena, such as gene-gene-drug interactions, in which variability in m...

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Detalles Bibliográficos
Autores principales: Zhou, Yitian, Lauschke, Volker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921140/
https://www.ncbi.nlm.nih.gov/pubmed/31890144
http://dx.doi.org/10.1016/j.csbj.2019.11.010