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New bioanalytical microemulsion Electrokinetic chromatography method for the simultaneous determination of Trifluridine with its metabolites and Tipiracil in rat plasma: Application to pharmacokinetic studies

A Microemulsion Electrokinetic Chromatography method coupled with diode array detector (MEEKC-DAD) was developed for the first time and found to be efficient, sensitive, and selective for the simultaneous analysis of Trifluridine (FTD), and its metabolites 5-(trifluoromethyl) uracil (FTY) and 5-carb...

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Detalles Bibliográficos
Autores principales: Hefnawy, Mohamed, Alzamil, Adeeba, Abuelizz, Hatem, AlShehri, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921166/
https://www.ncbi.nlm.nih.gov/pubmed/31885467
http://dx.doi.org/10.1016/j.jsps.2019.09.004