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Green synthesis and biological evaluation of novel 5-fluorouracil derivatives as potent anticancer agents
This study reports the formation of 5-FU co-crystals with four different pharmacologically safe co-formers; Urea, Thiourea, Acetanilide and Aspirin using methanol as a solvent. Two fabrication schemes were followed i.e., solid-state grinding protocol, in which API and co-formers were mixed through v...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921177/ https://www.ncbi.nlm.nih.gov/pubmed/31885476 http://dx.doi.org/10.1016/j.jsps.2019.09.013 |