A 2,3-diphenylpyrido[1,2-a] pyrimidin-4-one derivative inhibits specific angiogenic factors induced by TNF-α

Low-grade chronic inflammation is a key process of angiogenesis in tumour progression. We investigated whether a synthetic analogue of apigenin, the 2-(3,4-dimethoxyphenyl)-3-phenyl-4H-pyrido[1,2-a] pyrimidin-4-one (called DB103), interfered with the mechanisms involved in the angiogenic process ind...

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Detalles Bibliográficos
Autores principales: Del Turco, Serena, Quattrini, Luca, Colucci, Rocchina, Gaggini, Melania, La Motta, Concettina, Basta, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921196/
https://www.ncbi.nlm.nih.gov/pubmed/31885477
http://dx.doi.org/10.1016/j.jsps.2019.09.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921196/
https://www.ncbi.nlm.nih.gov/pubmed/31885477
http://dx.doi.org/10.1016/j.jsps.2019.09.014

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