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Integrated miRNA and mRNA expression profiling identifies novel targets and pathological mechanisms in autoimmune thyroid diseases

BACKGROUND: The mechanisms underlying autoimmune thyroid disease (AITD) remain elusive. Identification of such mechanisms would reveal novel and/or better therapeutic targets. Here, we use integrated analysis of miRNAs and mRNAs expression profiling to identify potential therapeutic targets involved...

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Detalles Bibliográficos
Autores principales: Martínez-Hernández, Rebeca, Serrano-Somavilla, Ana, Ramos-Leví, Ana, Sampedro-Nuñez, Miguel, Lens-Pardo, Alberto, Muñoz De Nova, José Luis, Triviño, Juan Carlos, González, María Ujue, Torné, Lorena, Casares-Arias, Javier, Martín-Cófreces, Noa B., Sánchez-Madrid, Francisco, Marazuela, Mónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921241/
https://www.ncbi.nlm.nih.gov/pubmed/31735554
http://dx.doi.org/10.1016/j.ebiom.2019.10.061