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Noncytotoxic Pyrrolobenzodiazepine–Ciprofloxacin Conjugate with Activity against Mycobacterium tuberculosis

[Image: see text] The development of new antitubercular agents for the treatment of infections caused by multidrug-resistant (MDR) Mycobacterium tuberculosis is an urgent priority. Pyrrolobenzodiazepines (PBDs) are a promising class of antibacterial agents that were initially discovered and isolated...

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Detalles Bibliográficos
Autores principales: Picconi, Pietro, Jeeves, Rose, Moon, Christopher William, Jamshidi, Shirin, Nahar, Kazi S., Laws, Mark, Bacon, Joanna, Rahman, Khondaker Miraz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921268/
https://www.ncbi.nlm.nih.gov/pubmed/31867477
http://dx.doi.org/10.1021/acsomega.9b00834