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Early active immunization with Aβ(3–10)-KLH vaccine reduces tau phosphorylation in the hippocampus and protects cognition of mice
Active and passive anti-Aβ immunotherapies have successfully been used for the prevention and treatment of Alzheimer’s disease animal models. However, clinical use of these immunotherapies is not effective, because the vaccination is administered too late. At 1 month of age, 100 μL of Aβ(3–10)-KLH p...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921334/ https://www.ncbi.nlm.nih.gov/pubmed/31571664 http://dx.doi.org/10.4103/1673-5374.266061 |