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Transfer of mitochondria from mesenchymal stem cells derived from induced pluripotent stem cells attenuates hypoxia-ischemia-induced mitochondrial dysfunction in PC12 cells

Mitochondrial dysfunction in neurons has been implicated in hypoxia-ischemia-induced brain injury. Although mesenchymal stem cell therapy has emerged as a novel treatment for this pathology, the mechanisms are not fully understood. To address this issue, we first co-cultured 1.5 × 10(5) PC12 cells w...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Ye, Gen, Zhang, Yue-Lin, He, Hai-Wei, Yu, Bao-Qi, Hong, Yi-Mei, You, Wei, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921344/
https://www.ncbi.nlm.nih.gov/pubmed/31571658
http://dx.doi.org/10.4103/1673-5374.266058