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Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization

BACKGROUND: Alcohol intake is a well-known lifestyle risk factor for CRC, and an increasing number of studies have revealed that alcohol intake is also tightly associated with CRC metastasis. However, the effect of alcohol on CRC metastasis and its underlying mechanism remain unclear. METHODS: A ret...

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Detalles Bibliográficos
Autores principales: Zheng, Kehong, Yu, Jinlong, Chen, Zetao, Zhou, Rui, Lin, Chuang, Zhang, Yuxuan, Huang, Zonghai, Yu, Lina, Zhao, Liang, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921366/
https://www.ncbi.nlm.nih.gov/pubmed/31757777
http://dx.doi.org/10.1016/j.ebiom.2019.11.011