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Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder

BACKGROUND: Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections (UTIs), and fimbrial tip adhesins, play important roles in UPEC colonization. Few fimbrial tip adhesins and their receptors on host cells, which have the potential to be the therapeutic targets, have b...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Pei, Geng, Zhang, Lisong, Cao, Yang, Wang, Jingyu, Yu, Lu, Dianjun, Wei, Gao, Shan, Zhang, Zhi-Song, Yao, Zhi, Wang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921372/
https://www.ncbi.nlm.nih.gov/pubmed/31757778
http://dx.doi.org/10.1016/j.ebiom.2019.11.014