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Typhoidal Salmonella human challenge studies: ethical and practical challenges and considerations for low-resource settings

Typhoidal Salmonella is a major global problem affecting more than 12 million people annually. Controlled human infection models (CHIMs) in high-resource settings have had an important role in accelerating the development of conjugate vaccines against Salmonella Typhi. The typhoidal Salmonella model...

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Detalles Bibliográficos
Autores principales: Raymond, Meriel, Gibani, Malick M., Day, Nicholas P. J., Cheah, Phaik Yeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921376/
https://www.ncbi.nlm.nih.gov/pubmed/31852488
http://dx.doi.org/10.1186/s13063-019-3844-z